Symbol: Name: ID: |
CSRNP1 cysteine-serine-rich nuclear protein 1 GFS:3663 |
Gene name: | CSRNP1 |
Chromosome: | 3p22 |
Previous Symbols: | AXUD1 |
Previous Names: | AXIN1 up-regulated 1 |
Aliases: | URAX1, DKFZp566F164, FAM130B, TAIP-3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2387989 | Rat Genome Database ID: | RGD:1305999 |
HGNC ID: | HGNC:14300 | RefSeq IDs: | NM_033027 |
Entrez Gene ID: | 64651 | Ensembl Gene ID: | ENSG00000144655 |
VEGA IDs: | OTTHUMG00000131293 | UniProt ID: | Q96S65 |
UCSC ID: | uc003cjg.2 | OMIM ID: | 606458 |
Pubmed: | PMID11526492 PMID 17726538 | ||
CCDS IDs: | CCDSCCDS2682.1 |
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May have a tumor-suppressor function. May play a role in apoptosis.
Products for CSRNP1 gene
Catalog | Product Name | Application | Company |
GFS:E03663 | cysteine-serine-rich nuclear protein 1; ELISA kit | ELISA | n/a |
GFS:A03663 | cysteine-serine-rich nuclear protein 1; Anti | ANTIBODIES | n/a |
GFS:P03663 | cysteine-serine-rich nuclear protein 1; Protien | Protien | n/a |