Symbol: Name: ID: |
CCNE2 cyclin E2 GFS:5034 |
Gene name: | CCNE2 |
Chromosome: | 8q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CYCE2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1329034 | Rat Genome Database ID: | RGD:1307783 |
HGNC ID: | HGNC:1590 | RefSeq IDs: | NM_057749 |
Entrez Gene ID: | 9134 | Ensembl Gene ID: | ENSG00000175305 |
VEGA IDs: | UniProt ID: | O96020 | |
UCSC ID: | uc003yhc.2 | OMIM ID: | 603775 |
Pubmed: | PMID9840927 PMID 9840943 | ||
CCDS IDs: | CCDSCCDS6264.1 |
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Essential for the control of the cell cycle at the late G1 and early S phase.
Products for CCNE2 gene
Catalog | Product Name | Application | Company |
GFS:E05034 | cyclin E2; ELISA kit | ELISA | n/a |
GFS:A05034 | cyclin E2; Anti | ANTIBODIES | n/a |
GFS:P05034 | cyclin E2; Protien | Protien | n/a |