Symbol: Name: ID: |
CFC1 cripto, FRL-1, cryptic family 1 GFS:7165 |
Gene name: | CFC1 |
Chromosome: | 2q21.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CRYPTIC, HTX2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109448 | Rat Genome Database ID: | RGD:1562188 |
HGNC ID: | HGNC:18292 | RefSeq IDs: | NM_032545 |
Entrez Gene ID: | 55997 | Ensembl Gene ID: | ENSG00000136698 |
VEGA IDs: | OTTHUMG00000131628 | UniProt ID: | P0CG37 |
UCSC ID: | uc002trl.1 | OMIM ID: | 605194 |
Pubmed: | PMID11062482 PMID 10858660 | ||
CCDS IDs: | CCDSCCDS2162.1 |
This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development. (provided by RefSeq)
Function: NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.
Products for CFC1 gene
Catalog | Product Name | Application | Company |
GFS:E07165 | cripto, FRL-1, cryptic family 1; ELISA kit | ELISA | n/a |
GFS:A07165 | cripto, FRL-1, cryptic family 1; Anti | ANTIBODIES | n/a |
GFS:P07165 | cripto, FRL-1, cryptic family 1; Protien | Protien | n/a |