Symbol: Name: ID: |
CRNN cornulin GFS:2117 |
Gene name: | CRNN |
Chromosome: | 1q21 |
Previous Symbols: | C1orf10 |
Previous Names: | chromosome 1 open reading frame 10 |
Aliases: | Sep-53 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2685861 | Rat Genome Database ID: | RGD:1311778 |
HGNC ID: | HGNC:1230 | RefSeq IDs: | NM_016190 |
Entrez Gene ID: | 49860 | Ensembl Gene ID: | ENSG00000143536 |
VEGA IDs: | OTTHUMG00000012383 | UniProt ID: | Q9UBG3 |
UCSC ID: | uc001ezx.2 | OMIM ID: | 611312 |
Pubmed: | PMID11056050 PMID 15854041 | ||
CCDS IDs: | CCDSCCDS1010.1 |
The CRNN encodes a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest.
Products for CRNN gene
Catalog | Product Name | Application | Company |
GFS:E02117 | cornulin; ELISA kit | ELISA | n/a |
GFS:A02117 | cornulin; Anti | ANTIBODIES | n/a |
GFS:P02117 | cornulin; Protien | Protien | n/a |