| Symbol: Name: ID: |
COTL1 coactosin-like 1 (Dictyostelium) GFS:7177 |
| Gene name: | COTL1 |
| Chromosome: | 16q24.1 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | CLP |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1919292 | Rat Genome Database ID: | RGD:1305498 |
| HGNC ID: | HGNC:18304 | RefSeq IDs: | NM_021149 |
| Entrez Gene ID: | 23406 | Ensembl Gene ID: | ENSG00000103187 |
| VEGA IDs: | OTTHUMG00000137634 | UniProt ID: | Q14019 |
| UCSC ID: | uc002fid.2 | OMIM ID: | 606748 |
| Pubmed: | PMID10051563 PMID 9326934 PMID 16924104 | ||
| CCDS IDs: | CCDSCCDS10947.1 | ||
Coactosin-like protein is a protein that in humans is encoded by the COTL1 gene.
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.
Products for COTL1 gene
| Catalog | Product Name | Application | Company |
| GFS:E07177 | coactosin-like 1 (Dictyostelium); ELISA kit | ELISA | n/a |
| GFS:A07177 | coactosin-like 1 (Dictyostelium); Anti | ANTIBODIES | n/a |
| GFS:P07177 | coactosin-like 1 (Dictyostelium); Protien | Protien | n/a |
