Symbol: Name: ID: |
CCKAR cholecystokinin A receptor GFS:4866 |
Gene name: | CCKAR |
Chromosome: | 4 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99478 | Rat Genome Database ID: | RGD:2289 |
HGNC ID: | HGNC:1570 | RefSeq IDs: | NM_000730 |
Entrez Gene ID: | 886 | Ensembl Gene ID: | ENSG00000163394 |
VEGA IDs: | OTTHUMG00000128567 | UniProt ID: | P32238 |
UCSC ID: | uc003gse.1 | OMIM ID: | 118444 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS3438.1 |
The Cholecystokinin A receptor is a human protein, also known as CCKAR or CCK1, with CCK1 now being the IUPHAR-recommended name.
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Products for CCKAR gene
Catalog | Product Name | Application | Company |
GFS:E04866 | cholecystokinin A receptor; ELISA kit | ELISA | n/a |
GFS:A04866 | cholecystokinin A receptor; Anti | ANTIBODIES | n/a |
GFS:P04866 | cholecystokinin A receptor; Protien | Protien | n/a |