Symbol: Name: ID: |
CLIC4 chloride intracellular channel 4 GFS:3072 |
Gene name: | CLIC4 |
Chromosome: | 1p |
Previous Symbols: | |
Previous Names: | |
Aliases: | DKFZP566G223, CLIC4L, P64H1, H1, huH1, p64H1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1352754 | Rat Genome Database ID: | RGD:61857 |
HGNC ID: | HGNC:13518 | RefSeq IDs: | NM_013943 |
Entrez Gene ID: | 25932 | Ensembl Gene ID: | ENSG00000169504 |
VEGA IDs: | OTTHUMG00000003327 | UniProt ID: | Q9Y696 |
UCSC ID: | uc001bjo.2 | OMIM ID: | 606536 |
Pubmed: | PMID9139710 PMID 10070163 | ||
CCDS IDs: | CCDSCCDS256.1 |
Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
Products for CLIC4 gene
Catalog | Product Name | Application | Company |
GFS:E03072 | chloride intracellular channel 4; ELISA kit | ELISA | n/a |
GFS:A03072 | chloride intracellular channel 4; Anti | ANTIBODIES | n/a |
GFS:P03072 | chloride intracellular channel 4; Protien | Protien | n/a |