Symbol: Name: ID: |
CHIA chitinase, acidic GFS:6488 |
Gene name: | CHIA |
Chromosome: | 1p13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AMCase, TSA1902, CHIT2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1932052 | Rat Genome Database ID: | RGD:1303058 |
HGNC ID: | HGNC:17432 | RefSeq IDs: | NM_021797 |
Entrez Gene ID: | 27159 | Ensembl Gene ID: | ENSG00000134216 |
VEGA IDs: | OTTHUMG00000011165 | UniProt ID: | Q9BZP6 |
UCSC ID: | uc001eas.2 | OMIM ID: | 606080 |
Pubmed: | PMID11085997 | ||
CCDS IDs: | CCDSCCDS832.1 CCDS CCDS41368.1 |
Function: Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Products for CHIA gene
Catalog | Product Name | Application | Company |
GFS:E06488 | chitinase, acidic; ELISA kit | ELISA | n/a |
GFS:A06488 | chitinase, acidic; Anti | ANTIBODIES | n/a |
GFS:P06488 | chitinase, acidic; Protien | Protien | n/a |