Symbol: Name: ID: |
CCBP2 chemokine binding protein 2 GFS:4828 |
Gene name: | CCBP2 |
Chromosome: | 3p21.3 |
Previous Symbols: | CMKBR9 |
Previous Names: | |
Aliases: | CCR10, D6, CCR9 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891697 | Rat Genome Database ID: | RGD:620323 |
HGNC ID: | HGNC:1565 | RefSeq IDs: | NM_001296 |
Entrez Gene ID: | 1238 | Ensembl Gene ID: | ENSG00000144648 |
VEGA IDs: | OTTHUMG00000133040 | UniProt ID: | O00590 |
UCSC ID: | uc003cme.2 | OMIM ID: | 602648 |
Pubmed: | PMID9364936 PMID 9405404 | ||
CCDS IDs: | CCDSCCDS2706.1 |
Chemokine-binding protein 2 is a protein that in humans is encoded by the CCBP2 gene.
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.
Products for CCBP2 gene
Catalog | Product Name | Application | Company |
GFS:E04828 | chemokine binding protein 2; ELISA kit | ELISA | n/a |
GFS:A04828 | chemokine binding protein 2; Anti | ANTIBODIES | n/a |
GFS:P04828 | chemokine binding protein 2; Protien | Protien | n/a |