| Symbol: Name: ID: |
CENPM centromere protein M GFS:7220 |
| Gene name: | CENPM |
| Chromosome: | 22q13.2 |
| Previous Symbols: | C22orf18 |
| Previous Names: | chromosome 22 open reading frame 18 |
| Aliases: | Pane1, CENP-M, MGC861 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1913820 | Rat Genome Database ID: | RGD:1307309 |
| HGNC ID: | HGNC:18352 | RefSeq IDs: | NM_001002876 |
| Entrez Gene ID: | 79019 | Ensembl Gene ID: | ENSG00000100162 |
| VEGA IDs: | OTTHUMG00000151277 | UniProt ID: | Q9NSP4 |
| UCSC ID: | uc003bbn.2 | OMIM ID: | 610152 |
| Pubmed: | PMID16622420 PMID 16622419 | ||
| CCDS IDs: | CCDSCCDS14025.1 CCDS CCDS46719.1 CCDS CCDS46720.1 | ||
Centromere protein M is a protein that in humans is encoded by the CENPM gene.
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008].
Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Products for CENPM gene
| Catalog | Product Name | Application | Company |
| GFS:E07220 | centromere protein M; ELISA kit | ELISA | n/a |
| GFS:A07220 | centromere protein M; Anti | ANTIBODIES | n/a |
| GFS:P07220 | centromere protein M; Protien | Protien | n/a |
