Symbol: Name: ID: |
CENPL centromere protein L GFS:6779 |
Gene name: | CENPL |
Chromosome: | 1q25.1 |
Previous Symbols: | C1orf155 |
Previous Names: | chromosome 1 open reading frame 155 |
Aliases: | dJ383J4.3, FLJ31044 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917704 | Rat Genome Database ID: | RGD:1311868 |
HGNC ID: | HGNC:17879 | RefSeq IDs: | NM_001127181 |
Entrez Gene ID: | 91687 | Ensembl Gene ID: | ENSG00000120334 |
VEGA IDs: | OTTHUMG00000034802 | UniProt ID: | Q8N0S6 |
UCSC ID: | uc001gjg.3 | OMIM ID: | 611503 |
Pubmed: | PMID16622420 PMID 16622419 | ||
CCDS IDs: | CCDSCCDS30938.1 CCDS CCDS44277.1 |
Centromere protein L is a protein that in humans is encoded by the CENPL gene.
CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) [PubMed 16622420].[supplied by OMIM, Mar 2008].
Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
Products for CENPL gene
Catalog | Product Name | Application | Company |
GFS:E06779 | centromere protein L; ELISA kit | ELISA | n/a |
GFS:A06779 | centromere protein L; Anti | ANTIBODIES | n/a |
GFS:P06779 | centromere protein L; Protien | Protien | n/a |