Symbol: Name: ID: |
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 GFS:7035 |
Gene name: | CEACAM3 |
Chromosome: | 19q13.2 |
Previous Symbols: | CGM1 |
Previous Names: | |
Aliases: | CD66d |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3646296 | Rat Genome Database ID: | RGD:2333 |
HGNC ID: | HGNC:1815 | RefSeq IDs: | NM_001815 |
Entrez Gene ID: | 1084 | Ensembl Gene ID: | ENSG00000170956 |
VEGA IDs: | OTTHUMG00000150142 | UniProt ID: | P40198 |
UCSC ID: | uc002orn.1 | OMIM ID: | 609142 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS12586.2 |
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a human gene.
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Products for CEACAM3 gene
Catalog | Product Name | Application | Company |
GFS:E07035 | carcinoembryonic antigen-related cell adhesion molecule 3; ELISA kit | ELISA | n/a |
GFS:A07035 | carcinoembryonic antigen-related cell adhesion molecule 3; Anti | ANTIBODIES | n/a |
GFS:P07035 | carcinoembryonic antigen-related cell adhesion molecule 3; Protien | Protien | n/a |