Symbol: Name: ID: |
CAPZB capping protein (actin filament) muscle Z-line, beta GFS:4197 |
Gene name: | CAPZB |
Chromosome: | 1p36.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104652 | Rat Genome Database ID: | RGD:1359099 |
HGNC ID: | HGNC:1491 | RefSeq IDs: | NM_004930 |
Entrez Gene ID: | 832 | Ensembl Gene ID: | ENSG00000077549 |
VEGA IDs: | OTTHUMG00000002556 | UniProt ID: | P47756 |
UCSC ID: | uc001bce.2 | OMIM ID: | 601572 |
Pubmed: | |||
CCDS IDs: |
F-actin-capping protein subunit beta is a protein that in humans is encoded by the CAPZB gene.
This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Apr 2011].
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Products for CAPZB gene
Catalog | Product Name | Application | Company |
GFS:E04197 | capping protein (actin filament) muscle Z-line, beta; ELISA kit | ELISA | n/a |
GFS:A04197 | capping protein (actin filament) muscle Z-line, beta; Anti | ANTIBODIES | n/a |
GFS:P04197 | capping protein (actin filament) muscle Z-line, beta; Protien | Protien | n/a |