Symbol: Name: ID: |
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 GFS:4187 |
Gene name: | CAPZA2 |
Chromosome: | 7q31.2-q31.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CAPZ, CAPPA2 |
Name Aliases: | F-actin capping protein alpha-2 subunit |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106222 | Rat Genome Database ID: | RGD:1549770 |
HGNC ID: | HGNC:1490 | RefSeq IDs: | NM_006136 |
Entrez Gene ID: | 830 | Ensembl Gene ID: | ENSG00000198898 |
VEGA IDs: | OTTHUMG00000023185 | UniProt ID: | P47755 |
UCSC ID: | uc003vil.2 | OMIM ID: | 601571 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS5768.1 |
F-actin-capping protein subunit alpha-2 is a protein that in humans is encoded by the CAPZA2 gene.
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008].
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Products for CAPZA2 gene
Catalog | Product Name | Application | Company |
GFS:E04187 | capping protein (actin filament) muscle Z-line, alpha 2; ELISA kit | ELISA | n/a |
GFS:A04187 | capping protein (actin filament) muscle Z-line, alpha 2; Anti | ANTIBODIES | n/a |
GFS:P04187 | capping protein (actin filament) muscle Z-line, alpha 2; Protien | Protien | n/a |