Symbol: Name: ID: |
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) GFS:4379 |
Gene name: | CASQ1 |
Chromosome: | 1q21 |
Previous Symbols: | CASQ |
Previous Names: | |
Aliases: | PDIB1 |
Name Aliases: | calsequestrin 1, fast-twitch, skeletal muscle, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1309468 | Rat Genome Database ID: | RGD:1586677 |
HGNC ID: | HGNC:1512 | RefSeq IDs: | NM_001231 |
Entrez Gene ID: | 844 | Ensembl Gene ID: | ENSG00000143318 |
VEGA IDs: | OTTHUMG00000031607 | UniProt ID: | P31415 |
UCSC ID: | uc010pja.1 | OMIM ID: | 114250 |
Pubmed: | PMID8406504 PMID 2321095 | ||
CCDS IDs: | CCDSCCDS1198.1 |
The protein encoded by this gene is a mitochondrial calcium-binding protein located in the luminal space of the terminal cisternae of the sarcoplasmic reticulum. The protein binds and putatively stores calcium ions. The protein is absent in patients with Duchenne and Becker types of muscular dystrophy. [provided by RefSeq, Jul 2008].
Function: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
Products for CASQ1 gene
Catalog | Product Name | Application | Company |
GFS:E04379 | calsequestrin 1 (fast-twitch, skeletal muscle); ELISA kit | ELISA | n/a |
GFS:A04379 | calsequestrin 1 (fast-twitch, skeletal muscle); Anti | ANTIBODIES | n/a |
GFS:P04379 | calsequestrin 1 (fast-twitch, skeletal muscle); Protien | Protien | n/a |