Symbol: Name: ID: |
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated GFS:4764 |
Gene name: | CABYR |
Chromosome: | 18q11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FSP-2, CBP86, CT88 |
Name Aliases: | fibrousheathin 2, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1918382 | Rat Genome Database ID: | RGD:1585413 |
HGNC ID: | HGNC:15569 | RefSeq IDs: | NM_012189 |
Entrez Gene ID: | 26256 | Ensembl Gene ID: | ENSG00000154040 |
VEGA IDs: | OTTHUMG00000037365 | UniProt ID: | O75952 |
UCSC ID: | uc002kux.2 | OMIM ID: | 612135 |
Pubmed: | PMID11820818 PMID 17317841 PMID 16139264 | ||
CCDS IDs: | CCDSCCDS11881.1 CCDS CCDS11882.1 CCDS CCDS11883.1 CCDS CCDS42420.1 CCDS CCDS45840.1 |
Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene.
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized. [provided by RefSeq, Jul 2008].
Function: May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
Products for CABYR gene
Catalog | Product Name | Application | Company |
GFS:E04764 | calcium binding tyrosine-(Y)-phosphorylation regulated; ELISA kit | ELISA | n/a |
GFS:A04764 | calcium binding tyrosine-(Y)-phosphorylation regulated; Anti | ANTIBODIES | n/a |
GFS:P04764 | calcium binding tyrosine-(Y)-phosphorylation regulated; Protien | Protien | n/a |