Symbol: Name: ID: |
ARPP21 cAMP-regulated phosphoprotein, 21kDa GFS:6057 |
Gene name: | ARPP21 |
Chromosome: | 3p24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ARPP-21, TARPP, R3HDM3 |
Name Aliases: | R3H domain containing 3 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107562 | Rat Genome Database ID: | RGD:1593239 |
HGNC ID: | HGNC:16968 | RefSeq IDs: | NM_001025068 |
Entrez Gene ID: | 10777 | Ensembl Gene ID: | ENSG00000172995 |
VEGA IDs: | OTTHUMG00000130795 | UniProt ID: | Q9UBL0 |
UCSC ID: | OMIM ID: | 605488 | |
Pubmed: | PMID8120638 | ||
CCDS IDs: | CCDSCCDS2661.1 CCDS CCDS43063.1 |
Cyclic AMP-regulated phosphoprotein, 21 kD, also known as ARPP-21, is a human gene.
The 21-kD cAMP-regulated phosphoprotein (ARPP21), also known as regulator of calmodulin (CaM; MIM 114180) signaling (RCS), plays a central role in integration of key neurotransmitter inputs into medium spiny neurons through its regulation of CaM-dependent kinase I (CaMKI) and protein phosphatase-2B (PP2B) (Rakhilin et al., 2004 (PubMed 15499021)).(supplied by OMIM)
Function: Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons (By similarity).
Products for ARPP21 gene
Catalog | Product Name | Application | Company |
GFS:E06057 | cAMP-regulated phosphoprotein, 21kDa; ELISA kit | ELISA | n/a |
GFS:A06057 | cAMP-regulated phosphoprotein, 21kDa; Anti | ANTIBODIES | n/a |
GFS:P06057 | cAMP-regulated phosphoprotein, 21kDa; Protien | Protien | n/a |