Symbol: Name: ID: |
BRWD1 bromodomain and WD repeat domain containing 1 GFS:2521 |
Gene name: | BRWD1 |
Chromosome: | 21q22.2 |
Previous Symbols: | C21orf107, WDR9 |
Previous Names: | chromosome 21 open reading frame 107, "WD repeat domain 9" |
Aliases: | FLJ11315, N143 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1890651 | Rat Genome Database ID: | RGD:1309030 |
HGNC ID: | HGNC:12760 | RefSeq IDs: | NM_001007246 |
Entrez Gene ID: | 54014 | Ensembl Gene ID: | ENSG00000185658 |
VEGA IDs: | OTTHUMG00000066030 | UniProt ID: | Q9NSI6 |
UCSC ID: | uc002yxk.1 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS13662.1 CCDS CCDS13663.1 CCDS CCDS33557.1 |
Bromodomain and WD repeat-containing protein 1 is a protein that in humans is encoded by the BRWD1 gene.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.
Function: May be a transcriptional activator. May be involved in chromatin remodeling (By similarity).
Products for BRWD1 gene
Catalog | Product Name | Application | Company |
GFS:E02521 | bromodomain and WD repeat domain containing 1; ELISA kit | ELISA | n/a |
GFS:A02521 | bromodomain and WD repeat domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P02521 | bromodomain and WD repeat domain containing 1; Protien | Protien | n/a |