Symbol: Name: ID: |
BPHL biphenyl hydrolase-like (serine hydrolase) GFS:851 |
Gene name: | BPHL |
Chromosome: | 6p25 |
Previous Symbols: | MCNAA |
Previous Names: | |
Aliases: | Bph-rp |
Name Aliases: | breast epithelial mucin-associated antigen |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915271 | Rat Genome Database ID: | RGD:1307572 |
HGNC ID: | HGNC:1094 | RefSeq IDs: | NM_004332 |
Entrez Gene ID: | 670 | Ensembl Gene ID: | ENSG00000137274 |
VEGA IDs: | OTTHUMG00000014140 | UniProt ID: | Q86WA6 |
UCSC ID: | uc003mva.2 | OMIM ID: | 603156 |
Pubmed: | PMID7759552 PMID 9721218 PMID 15832508 | ||
CCDS IDs: | CCDSCCDS4483.2 |
This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.
Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Products for BPHL gene
Catalog | Product Name | Application | Company |
GFS:E00851 | biphenyl hydrolase-like (serine hydrolase); ELISA kit | ELISA | n/a |
GFS:A00851 | biphenyl hydrolase-like (serine hydrolase); Anti | ANTIBODIES | n/a |
GFS:P00851 | biphenyl hydrolase-like (serine hydrolase); Protien | Protien | n/a |