| Symbol: Name: ID: |
BCO2 beta-carotene oxygenase 2 GFS:7351 |
| Gene name: | BCO2 |
| Chromosome: | 11q22.3-q23.1 |
| Previous Symbols: | BCDO2 |
| Previous Names: | beta-carotene dioxygenase 2 |
| Aliases: | FLJ34464, B-DIOX-II |
| Name Aliases: | beta-carotene 9',10' oxygenase |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2177469 | Rat Genome Database ID: | RGD:1309022 |
| HGNC ID: | HGNC:18503 | RefSeq IDs: | NM_001037290 |
| Entrez Gene ID: | 83875 | Ensembl Gene ID: | ENSG00000197580 |
| VEGA IDs: | OTTHUMG00000132995 | UniProt ID: | Q9BYV7 |
| UCSC ID: | uc001pnf.2 | OMIM ID: | 611740 |
| Pubmed: | PMID11278918 PMID 15983114 PMID 15949678 | ||
| CCDS IDs: | CCDSCCDS8358.2 CCDS CCDS41716.1 | ||
BCDO2 catalyzes the asymmetric oxidative cleavage of beta-carotene in carotene metabolism (Kiefer et al., 2001 [PubMed 11278918]).[supplied by OMIM, Mar 2008].
Function: Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.
Products for BCO2 gene
| Catalog | Product Name | Application | Company |
| GFS:E07351 | beta-carotene oxygenase 2; ELISA kit | ELISA | n/a |
| GFS:A07351 | beta-carotene oxygenase 2; Anti | ANTIBODIES | n/a |
| GFS:P07351 | beta-carotene oxygenase 2; Protien | Protien | n/a |
