Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene. This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Function: May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.