Symbol: Name: ID: |
ATL1 atlastin GTPase 1 GFS:1125 |
Gene name: | ATL1 |
Chromosome: | 14q21.3 |
Previous Symbols: | SPG3, SPG3A |
Previous Names: | spastic paraplegia 3A (autosomal dominant) |
Aliases: | FSP1, AD-FSP |
Name Aliases: | atlastin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921241 | Rat Genome Database ID: | RGD:1359232 |
HGNC ID: | HGNC:11231 | RefSeq IDs: | NM_001127713 |
Entrez Gene ID: | 51062 | Ensembl Gene ID: | ENSG00000198513 |
VEGA IDs: | OTTHUMG00000140297 | UniProt ID: | Q8WXF7 |
UCSC ID: | uc001wyd.3 | OMIM ID: | 606439 |
Pubmed: | PMID8252041 PMID 7825576 | ||
CCDS IDs: | CCDSCCDS9700.1 CCDS CCDS32077.1 |
Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene.[ The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.
Products for ATL1 gene
Catalog | Product Name | Application | Company |
GFS:E01125 | atlastin GTPase 1; ELISA kit | ELISA | n/a |
GFS:A01125 | atlastin GTPase 1; Anti | ANTIBODIES | n/a |
GFS:P01125 | atlastin GTPase 1; Protien | Protien | n/a |