| Symbol: Name: ID: |
AZIN1 antizyme inhibitor 1 GFS:5544 |
| Gene name: | AZIN1 |
| Chromosome: | 8p22-q21.3 |
| Previous Symbols: | OAZIN |
| Previous Names: | ornithine decarboxylase antizyme inhibitor |
| Aliases: | OAZI, ODC1L |
| Name Aliases: | ornithine decarboxylase 1-like |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1859169 | Rat Genome Database ID: | RGD:61934 |
| HGNC ID: | HGNC:16432 | RefSeq IDs: | NM_015878 |
| Entrez Gene ID: | 51582 | Ensembl Gene ID: | ENSG00000155096 |
| VEGA IDs: | UniProt ID: | O14977 | |
| UCSC ID: | uc003yky.2 | OMIM ID: | 607909 |
| Pubmed: | PMID9349715 PMID 9110174 | ||
| CCDS IDs: | CCDSCCDS6295.1 | ||
Antizyme inhibitor 1 is a protein that in humans is encoded by the AZIN1 gene.
Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Regulates cellular polyamine homeostasis (By similarity). Inhibits antizyme-dependent ornithine decarboxylase degradation by binding to antizyme.
Products for AZIN1 gene
| Catalog | Product Name | Application | Company |
| GFS:E05544 | antizyme inhibitor 1; ELISA kit | ELISA | n/a |
| GFS:A05544 | antizyme inhibitor 1; Anti | ANTIBODIES | n/a |
| GFS:P05544 | antizyme inhibitor 1; Protien | Protien | n/a |
