Symbol: Name: ID: |
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) GFS:4961 |
Gene name: | ANKRD1 |
Chromosome: | 10q23.33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | C-193, ALRP, CARP, CVARP, MCARP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1097717 | Rat Genome Database ID: | RGD:61989 |
HGNC ID: | HGNC:15819 | RefSeq IDs: | NM_014391 |
Entrez Gene ID: | 27063 | Ensembl Gene ID: | ENSG00000148677 |
VEGA IDs: | OTTHUMG00000018734 | UniProt ID: | Q15327 |
UCSC ID: | uc001khe.1 | OMIM ID: | 609599 |
Pubmed: | PMID7730328 | ||
CCDS IDs: | CCDSCCDS7412.1 |
Ankyrin repeat domain-containing protein 1 is a protein that in humans is encoded by the ANKRD1 gene.
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Products for ANKRD1 gene
Catalog | Product Name | Application | Company |
GFS:E04961 | ankyrin repeat domain 1 (cardiac muscle); ELISA kit | ELISA | n/a |
GFS:A04961 | ankyrin repeat domain 1 (cardiac muscle); Anti | ANTIBODIES | n/a |
GFS:P04961 | ankyrin repeat domain 1 (cardiac muscle); Protien | Protien | n/a |