Symbol: Name: ID: |
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 GFS:3060 |
Gene name: | ASZ1 |
Chromosome: | 7q31.2 |
Previous Symbols: | C7orf7, ANKL1 |
Previous Names: | ankyrin-like 1 |
Aliases: | Orf3, GASZ, ALP1, CT1.19 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921318 | Rat Genome Database ID: | RGD:621579 |
HGNC ID: | HGNC:1350 | RefSeq IDs: | NM_130768 |
Entrez Gene ID: | 136991 | Ensembl Gene ID: | ENSG00000154438 |
VEGA IDs: | OTTHUMG00000064565 | UniProt ID: | Q8WWH4 |
UCSC ID: | uc003vjb.2 | OMIM ID: | 605797 |
Pubmed: | PMID12040005 PMID 11279520 | ||
CCDS IDs: | CCDSCCDS5772.1 |
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 is a protein that in humans is encoded by the ASZ1 gene.
Function: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).
Products for ASZ1 gene
Catalog | Product Name | Application | Company |
GFS:E03060 | ankyrin repeat, SAM and basic leucine zipper domain containing 1; ELISA kit | ELISA | n/a |
GFS:A03060 | ankyrin repeat, SAM and basic leucine zipper domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P03060 | ankyrin repeat, SAM and basic leucine zipper domain containing 1; Protien | Protien | n/a |