Symbol: Name: ID: |
AMN amnionless homolog (mouse) GFS:3906 |
Gene name: | AMN |
Chromosome: | 14q32.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1934943 | Rat Genome Database ID: | RGD:1308634 |
HGNC ID: | HGNC:14604 | RefSeq IDs: | NM_030943 |
Entrez Gene ID: | 81693 | Ensembl Gene ID: | ENSG00000166126 |
VEGA IDs: | UniProt ID: | Q9BXJ7 | |
UCSC ID: | uc001ymg.3 | OMIM ID: | 605799 |
Pubmed: | PMID11279523 | ||
CCDS IDs: | CCDSCCDS9977.1 |
Amnionless is a protein that in humans is encoded by the AMN gene.
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008].
Function: Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity).
Products for AMN gene
Catalog | Product Name | Application | Company |
GFS:E03906 | amnionless homolog (mouse); ELISA kit | ELISA | n/a |
GFS:A03906 | amnionless homolog (mouse); Anti | ANTIBODIES | n/a |
GFS:P03906 | amnionless homolog (mouse); Protien | Protien | n/a |