Symbol: Name: ID: |
ACSL6 acyl-CoA synthetase long-chain family member 6 GFS:5604 |
Gene name: | ACSL6 |
Chromosome: | 5q31 |
Previous Symbols: | FACL6 |
Previous Names: | fatty-acid-Coenzyme A ligase, long-chain 6 |
Aliases: | KIAA0837, ACS2, LACS5, LACS2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:894291 | Rat Genome Database ID: | RGD:69403 |
HGNC ID: | HGNC:16496 | RefSeq IDs: | NM_001009185 |
Entrez Gene ID: | 23305 | Ensembl Gene ID: | ENSG00000164398 |
VEGA IDs: | OTTHUMG00000150692 | UniProt ID: | Q9UKU0 |
UCSC ID: | uc003kvy.1 | OMIM ID: | 604443 |
Pubmed: | PMID10502316 PMID 10548543 | ||
CCDS IDs: | CCDSCCDS34228.1 CCDS CCDS34229.1 |
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011].
Function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Products for ACSL6 gene
Catalog | Product Name | Application | Company |
GFS:E05604 | acyl-CoA synthetase long-chain family member 6; ELISA kit | ELISA | n/a |
GFS:A05604 | acyl-CoA synthetase long-chain family member 6; Anti | ANTIBODIES | n/a |
GFS:P05604 | acyl-CoA synthetase long-chain family member 6; Protien | Protien | n/a |