Symbol: Name: ID: |
ACTL6B actin-like 6B GFS:5131 |
Gene name: | ACTL6B |
Chromosome: | 7q22 |
Previous Symbols: | ACTL6 |
Previous Names: | actin-like 6 |
Aliases: | BAF53B |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1933548 | Rat Genome Database ID: | RGD:1307763 |
HGNC ID: | HGNC:160 | RefSeq IDs: | NM_016188 |
Entrez Gene ID: | 51412 | Ensembl Gene ID: | ENSG00000077080 |
VEGA IDs: | UniProt ID: | O94805 | |
UCSC ID: | uc003uvy.2 | OMIM ID: | 612458 |
Pubmed: | PMID9799793 | ||
CCDS IDs: | CCDSCCDS5702.1 |
Actin-like protein 6B is a protein that in humans is encoded by the ACTL6B gene.
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for ACTL6B gene
Catalog | Product Name | Application | Company |
GFS:E05131 | actin-like 6B; ELISA kit | ELISA | n/a |
GFS:A05131 | actin-like 6B; Anti | ANTIBODIES | n/a |
GFS:P05131 | actin-like 6B; Protien | Protien | n/a |