Symbol: Name: ID: |
ACR acrosin GFS:2381 |
Gene name: | ACR |
Chromosome: | 22q13-qter |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | preproacrosin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:87884 | Rat Genome Database ID: | RGD:2024 |
HGNC ID: | HGNC:126 | RefSeq IDs: | NM_001097 |
Entrez Gene ID: | Ensembl Gene ID: | ENSG00000100312 | |
VEGA IDs: | OTTHUMG00000150155 | UniProt ID: | P10323 |
UCSC ID: | uc003bnh.3 | OMIM ID: | 102480 |
Pubmed: | PMID2298447 PMID 12398221 | ||
CCDS IDs: | CCDSCCDS14101.1 |
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
Products for ACR gene
Catalog | Product Name | Application | Company |
GFS:E02381 | acrosin; ELISA kit | ELISA | n/a |
GFS:A02381 | acrosin; Anti | ANTIBODIES | n/a |
GFS:P02381 | acrosin; Protien | Protien | n/a |