Symbol: Name: ID: |
ZIC3 Zic family member 3 (odd-paired homolog, Drosophila) GFS:2621 |
Gene name: | ZIC3 |
Chromosome: | Xq24-q27.1 |
Previous Symbols: | HTX1 |
Previous Names: | heterotaxy 1 |
Aliases: | HTX, ZNF203 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106676 | Rat Genome Database ID: | RGD:1561261 |
HGNC ID: | HGNC:12874 | RefSeq IDs: | NM_003413 |
Entrez Gene ID: | 7547 | Ensembl Gene ID: | ENSG00000156925 |
VEGA IDs: | OTTHUMG00000022525 | UniProt ID: | O60481 |
UCSC ID: | uc004fak.2 | OMIM ID: | 300265 |
Pubmed: | PMID8298651 PMID 7747776 | ||
CCDS IDs: | CCDSCCDS14663.1 |
Zinc finger protein ZIC 3 is a protein that in humans is encoded by the ZIC3 gene.
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
Products for ZIC3 gene
Catalog | Product Name | Application | Company |
GFS:E02621 | Zic family member 3 (odd-paired homolog, Drosophila); ELISA kit | ELISA | n/a |
GFS:A02621 | Zic family member 3 (odd-paired homolog, Drosophila); Anti | ANTIBODIES | n/a |
GFS:P02621 | Zic family member 3 (odd-paired homolog, Drosophila); Protien | Protien | n/a |