Symbol: Name: ID: |
ZWINT ZW10 interactor GFS:2856 |
Gene name: | ZWINT |
Chromosome: | 10q21-q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KNTC2AP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1289227 | Rat Genome Database ID: | |
HGNC ID: | HGNC:13195 | RefSeq IDs: | NM_001005413 |
Entrez Gene ID: | 11130 | Ensembl Gene ID: | ENSG00000122952 |
VEGA IDs: | OTTHUMG00000018261 | UniProt ID: | O95229 |
UCSC ID: | uc001jka.1 | OMIM ID: | 609177 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS7249.1 CCDS CCDS31205.1 |
ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene.
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. equired to target ZW10 to the kinetochore at prometaphase.
Products for ZWINT gene
Catalog | Product Name | Application | Company |
GFS:E02856 | ZW10 interactor; ELISA kit | ELISA | n/a |
GFS:A02856 | ZW10 interactor; Anti | ANTIBODIES | n/a |
GFS:P02856 | ZW10 interactor; Protien | Protien | n/a |