Symbol: Name: ID: |
VSIG4 V-set and immunoglobulin domain containing 4 GFS:6125 |
Gene name: | VSIG4 |
Chromosome: | Xq12-q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Z39IG |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2679720 | Rat Genome Database ID: | RGD:1564659 |
HGNC ID: | HGNC:17032 | RefSeq IDs: | NM_001100431 |
Entrez Gene ID: | 11326 | Ensembl Gene ID: | ENSG00000155659 |
VEGA IDs: | OTTHUMG00000021727 | UniProt ID: | Q9Y279 |
UCSC ID: | uc004dwh.2 | OMIM ID: | 300353 |
Pubmed: | PMID10899594 PMID 11004523 PMID 17016555 PMID 17016562 | ||
CCDS IDs: | CCDSCCDS14383.1 CCDS CCDS48132.1 |
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Function: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
Products for VSIG4 gene
Catalog | Product Name | Application | Company |
GFS:E06125 | V-set and immunoglobulin domain containing 4; ELISA kit | ELISA | n/a |
GFS:A06125 | V-set and immunoglobulin domain containing 4; Anti | ANTIBODIES | n/a |
GFS:P06125 | V-set and immunoglobulin domain containing 4; Protien | Protien | n/a |