| Symbol: Name: ID: |
UBXN1 UBX domain protein 1 GFS:7259 |
| Gene name: | UBXN1 |
| Chromosome: | 11q23 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | LOC51035, 2B28, UBXD10, SAKS1 |
| Name Aliases: | SAPK substrate protein 1 |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1289301 | Rat Genome Database ID: | RGD:1309471 |
| HGNC ID: | HGNC:18402 | RefSeq IDs: | NM_015853 |
| Entrez Gene ID: | 51035 | Ensembl Gene ID: | ENSG00000162191 |
| VEGA IDs: | UniProt ID: | Q04323 | |
| UCSC ID: | uc001nuj.2 | OMIM ID: | |
| Pubmed: | PMID12838346 PMID 20351172 | ||
| CCDS IDs: | CCDSCCDS8029.1 | ||
Function: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.
Products for UBXN1 gene
| Catalog | Product Name | Application | Company |
| GFS:E07259 | UBX domain protein 1; ELISA kit | ELISA | n/a |
| GFS:A07259 | UBX domain protein 1; Anti | ANTIBODIES | n/a |
| GFS:P07259 | UBX domain protein 1; Protien | Protien | n/a |
