Symbol: Name: ID: |
TSFM Ts translation elongation factor, mitochondrial GFS:2171 |
Gene name: | TSFM |
Chromosome: | 12q14.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | EF-Tsmt, EF-TS |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913649 | Rat Genome Database ID: | |
HGNC ID: | HGNC:12367 | RefSeq IDs: | NM_001172695 |
Entrez Gene ID: | 10102 | Ensembl Gene ID: | ENSG00000123297 |
VEGA IDs: | OTTHUMG00000153042 | UniProt ID: | P43897 |
UCSC ID: | uc001sqi.2 | OMIM ID: | 604723 |
Pubmed: | PMID7615523 | ||
CCDS IDs: | CCDSCCDS8958.2 |
Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
Products for TSFM gene
Catalog | Product Name | Application | Company |
GFS:E02171 | Ts translation elongation factor, mitochondrial; ELISA kit | ELISA | n/a |
GFS:A02171 | Ts translation elongation factor, mitochondrial; Anti | ANTIBODIES | n/a |
GFS:P02171 | Ts translation elongation factor, mitochondrial; Protien | Protien | n/a |