| Symbol: Name: ID: |
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) GFS:2283 |
| Gene name: | TPX2 |
| Chromosome: | 20q11.2 |
| Previous Symbols: | C20orf2, C20orf1 |
| Previous Names: | chromosome 20 open reading frame 1 |
| Aliases: | p100, DIL-2 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1919369 | Rat Genome Database ID: | RGD:1311894 |
| HGNC ID: | HGNC:1249 | RefSeq IDs: | NM_012112 |
| Entrez Gene ID: | 22974 | Ensembl Gene ID: | ENSG00000088325 |
| VEGA IDs: | OTTHUMG00000032190 | UniProt ID: | Q9ULW0 |
| UCSC ID: | uc002wwp.1 | OMIM ID: | 605917 |
| Pubmed: | PMID9207457 PMID 10393424 | ||
| CCDS IDs: | CCDSCCDS13190.1 | ||
Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene.
Function: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Products for TPX2 gene
| Catalog | Product Name | Application | Company |
| GFS:E02283 | TPX2, microtubule-associated, homolog (Xenopus laevis); ELISA kit | ELISA | n/a |
| GFS:A02283 | TPX2, microtubule-associated, homolog (Xenopus laevis); Anti | ANTIBODIES | n/a |
| GFS:P02283 | TPX2, microtubule-associated, homolog (Xenopus laevis); Protien | Protien | n/a |
