Symbol: Name: ID: |
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 GFS:1620 |
Gene name: | TIAL1 |
Chromosome: | 10q |
Previous Symbols: | |
Previous Names: | TIA1 cytotoxic granule-associated RNA-binding protein-like 1 |
Aliases: | TIAR |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107913 | Rat Genome Database ID: | RGD:1595845 |
HGNC ID: | HGNC:11804 | RefSeq IDs: | NM_001033925 |
Entrez Gene ID: | 7073 | Ensembl Gene ID: | ENSG00000151923 |
VEGA IDs: | OTTHUMG00000019156 | UniProt ID: | Q01085 |
UCSC ID: | uc001lej.1 | OMIM ID: | 603413 |
Pubmed: | PMID1326761 | ||
CCDS IDs: | CCDSCCDS7613.1 CCDS CCDS31295.1 |
Nucleolysin TIAR is a protein that in humans is encoded by the TIAL1 gene. The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq].
Function: RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Products for TIAL1 gene
Catalog | Product Name | Application | Company |
GFS:E01620 | TIA1 cytotoxic granule-associated RNA binding protein-like 1; ELISA kit | ELISA | n/a |
GFS:A01620 | TIA1 cytotoxic granule-associated RNA binding protein-like 1; Anti | ANTIBODIES | n/a |
GFS:P01620 | TIA1 cytotoxic granule-associated RNA binding protein-like 1; Protien | Protien | n/a |