Symbol: Name: ID: |
TBPL1 TBP-like 1 GFS:1440 |
Gene name: | TBPL1 |
Chromosome: | 6q22.1-q22.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | TLP, STUD, TRF2, TLF |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1339946 | Rat Genome Database ID: | RGD:1597456 |
HGNC ID: | HGNC:11589 | RefSeq IDs: | NM_004865 |
Entrez Gene ID: | 9519 | Ensembl Gene ID: | ENSG00000028839 |
VEGA IDs: | OTTHUMG00000015609 | UniProt ID: | P62380 |
UCSC ID: | uc003qel.2 | OMIM ID: | 605521 |
Pubmed: | PMID10082669 PMID 10220372 PMID 15767669 | ||
CCDS IDs: | CCDSCCDS5168.1 |
TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 gene. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for TBPL1 gene
Catalog | Product Name | Application | Company |
GFS:E01440 | TBP-like 1; ELISA kit | ELISA | n/a |
GFS:A01440 | TBP-like 1; Anti | ANTIBODIES | n/a |
GFS:P01440 | TBP-like 1; Protien | Protien | n/a |