Symbol: Name: ID: |
TBR1 T-box, brain, 1 GFS:1441 |
Gene name: | TBR1 |
Chromosome: | 2q24.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107404 | Rat Genome Database ID: | RGD:1591773 |
HGNC ID: | HGNC:11590 | RefSeq IDs: | NM_006593 |
Entrez Gene ID: | 10716 | Ensembl Gene ID: | ENSG00000136535 |
VEGA IDs: | OTTHUMG00000153888 | UniProt ID: | Q16650 |
UCSC ID: | uc002ubw.1 | OMIM ID: | 604616 |
Pubmed: | PMID7619531 | ||
CCDS IDs: | CCDSCCDS33310.1 |
The TBR1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq].
Function: Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.
Products for TBR1 gene
Catalog | Product Name | Application | Company |
GFS:E01441 | T-box, brain, 1; ELISA kit | ELISA | n/a |
GFS:A01441 | T-box, brain, 1; Anti | ANTIBODIES | n/a |
GFS:P01441 | T-box, brain, 1; Protien | Protien | n/a |