Symbol: Name: ID: |
SAP30 Sin3A-associated protein, 30kDa GFS:471 |
Gene name: | SAP30 |
Chromosome: | 4q34.1 |
Previous Symbols: | |
Previous Names: | sin3A-associated protein, 30kDa |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929129 | Rat Genome Database ID: | |
HGNC ID: | HGNC:10532 | RefSeq IDs: | NM_003864 |
Entrez Gene ID: | 8819 | Ensembl Gene ID: | ENSG00000164105 |
VEGA IDs: | UniProt ID: | O75446 | |
UCSC ID: | uc003itd.2 | OMIM ID: | 603378 |
Pubmed: | PMID9651585 | ||
CCDS IDs: | CCDSCCDS3817.1 |
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones
Products for SAP30 gene
Catalog | Product Name | Application | Company |
GFS:E00471 | Sin3A-associated protein, 30kDa; ELISA kit | ELISA | n/a |
GFS:A00471 | Sin3A-associated protein, 30kDa; Anti | ANTIBODIES | n/a |
GFS:P00471 | Sin3A-associated protein, 30kDa; Protien | Protien | n/a |