Symbol: Name: ID: |
SUN1 Sad1 and UNC84 domain containing 1 GFS:7431 |
Gene name: | SUN1 |
Chromosome: | 7p22.3 |
Previous Symbols: | UNC84A |
Previous Names: | unc-84 homolog A (C. elegans) |
Aliases: | KIAA0810, FLJ12407 |
Name Aliases: | Sad1 unc-84 domain protein 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1924303 | Rat Genome Database ID: | RGD:1359142 |
HGNC ID: | HGNC:18587 | RefSeq IDs: | NM_001130965 |
Entrez Gene ID: | 23353 | Ensembl Gene ID: | ENSG00000164828 |
VEGA IDs: | OTTHUMG00000151426 | UniProt ID: | O94901 |
UCSC ID: | uc011jvp.1 | OMIM ID: | 607723 |
Pubmed: | PMID11593002 | ||
CCDS IDs: | CCDSCCDS43533.1 CCDS CCDS47525.1 |
Protein unc-84 homolog A is a protein that in humans is encoded by the UNC84A gene.
This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2010].
Function: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity).
Products for SUN1 gene
Catalog | Product Name | Application | Company |
GFS:E07431 | Sad1 and UNC84 domain containing 1; ELISA kit | ELISA | n/a |
GFS:A07431 | Sad1 and UNC84 domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P07431 | Sad1 and UNC84 domain containing 1; Protien | Protien | n/a |