Symbol: Name: ID: |
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 GFS:1017 |
Gene name: | SMARCE1 |
Chromosome: | 17q21.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | BAF57 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927347 | Rat Genome Database ID: | RGD:1304726 |
HGNC ID: | HGNC:11109 | RefSeq IDs: | NM_003079 |
Entrez Gene ID: | 6605 | Ensembl Gene ID: | ENSG00000073584 |
VEGA IDs: | OTTHUMG00000133367 | UniProt ID: | Q969G3 |
UCSC ID: | uc002hux.2 | OMIM ID: | 603111 |
Pubmed: | PMID9435219 | ||
CCDS IDs: | CCDSCCDS11370.1 |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 is a protein that in humans is encoded by the SMARCE1 gene. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SMARCE1 gene
Catalog | Product Name | Application | Company |
GFS:E01017 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; ELISA kit | ELISA | n/a |
GFS:A01017 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; Anti | ANTIBODIES | n/a |
GFS:P01017 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; Protien | Protien | n/a |