Symbol: Name: ID: |
SWAP70 SWAP switching B-cell complex 70kDa subunit GFS:6164 |
Gene name: | SWAP70 |
Chromosome: | 11p15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0640, SWAP-70 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1298390 | Rat Genome Database ID: | RGD:1305579 |
HGNC ID: | HGNC:17070 | RefSeq IDs: | NM_015055 |
Entrez Gene ID: | 23075 | Ensembl Gene ID: | ENSG00000133789 |
VEGA IDs: | UniProt ID: | Q9UH65 | |
UCSC ID: | uc001mhw.2 | OMIM ID: | 604762 |
Pubmed: | PMID9734811 PMID 10681448 | ||
CCDS IDs: | CCDSCCDS31426.1 |
Switch-associated protein 70 is a protein that in humans and other mammals is encoded by the SWAP70 gene.
Function: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
Products for SWAP70 gene
Catalog | Product Name | Application | Company |
GFS:E06164 | SWAP switching B-cell complex 70kDa subunit; ELISA kit | ELISA | n/a |
GFS:A06164 | SWAP switching B-cell complex 70kDa subunit; Anti | ANTIBODIES | n/a |
GFS:P06164 | SWAP switching B-cell complex 70kDa subunit; Protien | Protien | n/a |