Symbol: Name: ID: |
SON SON DNA binding protein GFS:1082 |
Gene name: | SON |
Chromosome: | 21q22.1-q22.2 |
Previous Symbols: | C21orf50 |
Previous Names: | |
Aliases: | DBP-5, NREBP, KIAA1019, BASS1, FLJ21099, FLJ33914 |
Name Aliases: | NRE-binding protein, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98353 | Rat Genome Database ID: | |
HGNC ID: | HGNC:11183 | RefSeq IDs: | NM_032195 |
Entrez Gene ID: | 6651 | Ensembl Gene ID: | ENSG00000159140 |
VEGA IDs: | OTTHUMG00000065806 | UniProt ID: | P18583 |
UCSC ID: | uc002yse.1 | OMIM ID: | 182465 |
Pubmed: | PMID8318737 | ||
CCDS IDs: | CCDSCCDS13629.1 CCDS CCDS13631.1 |
SON protein is a protein that in humans is encoded by the SON gene. The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq].
Represses hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. Binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3'. Might protect cells from apoptosis. Might be involved in pre-mRNA splicing (By similarity).
Products for SON gene
Catalog | Product Name | Application | Company |
GFS:E01082 | SON DNA binding protein; ELISA kit | ELISA | n/a |
GFS:A01082 | SON DNA binding protein; Anti | ANTIBODIES | n/a |
GFS:P01082 | SON DNA binding protein; Protien | Protien | n/a |