Symbol: Name: ID: |
SLU7 SLU7 splicing factor homolog (S. cerevisiae) GFS:6027 |
Gene name: | SLU7 |
Chromosome: | 5q33.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | 9G8 |
Name Aliases: | zinc knuckle motif containing |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385598 | Rat Genome Database ID: | RGD:631432 |
HGNC ID: | HGNC:16939 | RefSeq IDs: | NM_006425 |
Entrez Gene ID: | 10569 | Ensembl Gene ID: | ENSG00000164609 |
VEGA IDs: | OTTHUMG00000130324 | UniProt ID: | O95391 |
UCSC ID: | uc003lyg.2 | OMIM ID: | 605974 |
Pubmed: | PMID10197984 PMID 15728250 | ||
CCDS IDs: | CCDSCCDS4352.1 |
Pre-mRNA-splicing factor SLU7 is a protein that in humans is encoded by the SLU7 gene.
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008].
Function: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
Products for SLU7 gene
Catalog | Product Name | Application | Company |
GFS:E06027 | SLU7 splicing factor homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06027 | SLU7 splicing factor homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06027 | SLU7 splicing factor homolog (S. cerevisiae); Protien | Protien | n/a |