Symbol: Name: ID: |
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 GFS:6460 |
Gene name: | SRGAP1 |
Chromosome: | 12q13.13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA1304, ARHGAP13 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2152936 | Rat Genome Database ID: | RGD:1566260 |
HGNC ID: | HGNC:17382 | RefSeq IDs: | NM_020762 |
Entrez Gene ID: | 57522 | Ensembl Gene ID: | ENSG00000196935 |
VEGA IDs: | UniProt ID: | Q7Z6B7 | |
UCSC ID: | uc010ssp.1 | OMIM ID: | 606523 |
Pubmed: | PMID11672528 | ||
CCDS IDs: | CCDSCCDS8967.1 |
SLIT-ROBO Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the SRGAP1 gene.
Function: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Products for SRGAP1 gene
Catalog | Product Name | Application | Company |
GFS:E06460 | SLIT-ROBO Rho GTPase activating protein 1; ELISA kit | ELISA | n/a |
GFS:A06460 | SLIT-ROBO Rho GTPase activating protein 1; Anti | ANTIBODIES | n/a |
GFS:P06460 | SLIT-ROBO Rho GTPase activating protein 1; Protien | Protien | n/a |