Symbol: Name: ID: |
SCYL1 SCY1-like 1 (S. cerevisiae) GFS:3718 |
Gene name: | SCYL1 |
Chromosome: | 11q11-q12 |
Previous Symbols: | NTKL |
Previous Names: | N-terminal kinase-like |
Aliases: | HT019, P105, GKLP, NKTL, TAPK, TRAP, TEIF, MGC78454 |
Name Aliases: | teratoma-associated tyrosine kinase, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1931787 | Rat Genome Database ID: | RGD:1307330 |
HGNC ID: | HGNC:14372 | RefSeq IDs: | NM_001048218 |
Entrez Gene ID: | 57410 | Ensembl Gene ID: | ENSG00000142186 |
VEGA IDs: | UniProt ID: | Q96KG9 | |
UCSC ID: | uc001oea.1 | OMIM ID: | 607982 |
Pubmed: | PMID11118629 | ||
CCDS IDs: | CCDSCCDS41672.1 CCDS CCDS44646.1 |
SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution.
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Regulates COPI-mediated retrograde traffic. Has no detectable kinase activity in vitro
Function: Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region.
Products for SCYL1 gene
Catalog | Product Name | Application | Company |
GFS:E03718 | SCY1-like 1 (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A03718 | SCY1-like 1 (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P03718 | SCY1-like 1 (S. cerevisiae); Protien | Protien | n/a |