Symbol: Name: ID: |
SPDEF SAM pointed domain containing ets transcription factor GFS:6337 |
Gene name: | SPDEF |
Chromosome: | 6p21.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PDEF, bA375E1.3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1353422 | Rat Genome Database ID: | RGD:1594842 |
HGNC ID: | HGNC:17257 | RefSeq IDs: | NM_012391 |
Entrez Gene ID: | 25803 | Ensembl Gene ID: | ENSG00000124664 |
VEGA IDs: | OTTHUMG00000014548 | UniProt ID: | O95238 |
UCSC ID: | uc003ojq.1 | OMIM ID: | 608144 |
Pubmed: | PMID10625666 PMID 6857767 | ||
CCDS IDs: | CCDSCCDS4794.1 |
SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene.
PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.[supplied by OMIM, Apr 2004]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
Products for SPDEF gene
Catalog | Product Name | Application | Company |
GFS:E06337 | SAM pointed domain containing ets transcription factor; ELISA kit | ELISA | n/a |
GFS:A06337 | SAM pointed domain containing ets transcription factor; Anti | ANTIBODIES | n/a |
GFS:P06337 | SAM pointed domain containing ets transcription factor; Protien | Protien | n/a |