Symbol: Name: ID: |
S100B S100 calcium binding protein B GFS:446 |
Gene name: | S100B |
Chromosome: | 21q22.3 |
Previous Symbols: | |
Previous Names: | S100 calcium binding protein, beta (neural) |
Aliases: | S100beta |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98217 | Rat Genome Database ID: | RGD:3615 |
HGNC ID: | HGNC:10500 | RefSeq IDs: | NM_006272 |
Entrez Gene ID: | 6285 | Ensembl Gene ID: | ENSG00000160307 |
VEGA IDs: | OTTHUMG00000090715 | UniProt ID: | P04271 |
UCSC ID: | uc002zju.1 | OMIM ID: | 176990 |
Pubmed: | PMID2394738 PMID 1998503 | ||
CCDS IDs: | CCDSCCDS13736.1 |
The protein encoded by S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for S100B gene
Catalog | Product Name | Application | Company |
GFS:E00446 | S100 calcium binding protein B; ELISA kit | ELISA | n/a |
GFS:A00446 | S100 calcium binding protein B; Anti | ANTIBODIES | n/a |
GFS:P00446 | S100 calcium binding protein B; Protien | Protien | n/a |