Symbol: Name: ID: |
SAG S-antigen; retina and pineal gland (arrestin) GFS:461 |
Gene name: | SAG |
Chromosome: | 2q37.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ARRESTIN |
Name Aliases: | arrestin 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98227 | Rat Genome Database ID: | RGD:3619 |
HGNC ID: | HGNC:10521 | RefSeq IDs: | NM_000541 |
Entrez Gene ID: | 6295 | Ensembl Gene ID: | ENSG00000130561 |
VEGA IDs: | OTTHUMG00000153213 | UniProt ID: | P10523 |
UCSC ID: | uc002vuh.2 | OMIM ID: | 181031 |
Pubmed: | PMID2249983 | ||
CCDS IDs: | CCDSCCDS46545.1 |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SAG gene
Catalog | Product Name | Application | Company |
GFS:E00461 | S-antigen; retina and pineal gland (arrestin); ELISA kit | ELISA | n/a |
GFS:A00461 | S-antigen; retina and pineal gland (arrestin); Anti | ANTIBODIES | n/a |
GFS:P00461 | S-antigen; retina and pineal gland (arrestin); Protien | Protien | n/a |