RuvB-like 1 (E. coli) | RUVBL1 ELISA | RUVBL1 Antibody | RUVBL1 Protein

RuvB-like 1 (E. coli) Gene Detail

Symbol: Name: ID:	RUVBL1 RuvB-like 1 (E. coli) GFS:416
Gene name:	RUVBL1
Chromosome:	3q21
Previous Symbols:
Previous Names:	RuvB (E coli homolog)-like 1
Aliases:	TIP49, NMP238, RVB1, TIP49a, Pontin52, ECP54, TIH1, Rvb1, INO80H
Name Aliases:	pontin,
Locus Type:	gene with protein product

RuvB-like 1 (E. coli) External Links

Mouse Genome Database ID:	MGI:1928760	Rat Genome Database ID:	RGD:68373
HGNC ID:	HGNC:10474	RefSeq IDs:	NM_003707
Entrez Gene ID:	8607	Ensembl Gene ID:	ENSG00000175792
VEGA IDs:	OTTHUMG00000159658	UniProt ID:	Q9Y265
UCSC ID:	uc003ekh.2	OMIM ID:	603449
Pubmed:	PMID9774387 PMID 9588198
CCDS IDs:	CCDSCCDS3047.1

Aliases & Descriptions for RUVBL1 gene

(According to HGNC, Entrez Gene, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, OMIM, GeneLoc , and/or Ensembl, miRBase) About This Section

Summary for RUVBL1

UniProtKB/Swiss-Prot: RUVB1_HUMAN, Q9Y265

Function: Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex

Function: May be able to bind plasminogen at cell surface and enhance plasminogen activation

Function: Essential for cell proliferation
Gene Wiki entry for RUVBL1 (RuvB-like 1)

Summaries
for RUVBL1 gene

Products for RUVBL1 gene

(SPECIES:Human;Rat;Mouse and other species fluids)

Catalog	Product Name	Application	Company
GFS:E00416	RuvB-like 1 (E. coli); ELISA kit	ELISA	n/a
GFS:A00416	RuvB-like 1 (E. coli); Anti	ANTIBODIES	n/a
GFS:P00416	RuvB-like 1 (E. coli); Protien	Protien	n/a

Products
with us for RUVBL1 gene